Sage Crossroads

 

 

Richard Miller

Ed2-Ksmall-IMG.jpg

Dr. Miller received his MD and PhD (in Human Genetics) at Yale University in 1976-77, undertook postdoctoral training at Harvard and Sloan-Kettering, and was on the Pathology Department faculty at Boston University from 1982-1990 before he moved to the University of Michigan. Dr. Miller's research work focuses on the effects of aging on T cell subset interactions and on the ways in which aging alters the earliest phases of the T cell activation process. Newer work in the laboratory deals with the genetics of lifespan and the development of new animal models for delayed aging. Dr. Miller also serves as Associate Director for Research in the Geriatrics Center, and is a Research Scientist at the Institute of Gerontology and the Ann Arbor VA Medical Center. He is the recipient of the 1994 AlliedSignal Award for Research in Aging and the 1997 Robert W. Kleemeier Award for Research in Aging.

Related Works
  • Eisenbraun, M. D., A. Tamir, and R. A. Miller. 2000. Altered composition of the immunological synapse in an anergic, age-dependent memory T cell subset. J. Immunology 164:6105-6112.

  • Flurkey, K., J. Papaconstantinou, R. A. Miller, and D. E. Harrison. 2001. Life span extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Natl. Acad. Sci. USA 98:6736-6741.

  • Miller, R. A. 2001. Biomarkers of aging: prediction of longevity using age-sensitive T cell subset determinations in a middle-aged, genetically heterogeneous mouse population. J. Gerontol. Biol. Sci. 56A:B180-B186.

  • Garcia, G. G., and R. A. Miller. 2001. Single-cell analyses reveal two defects in peptide-specific activation of naïve T cells from aged mice. J. Immunol. 166:3151-3157.

  • Dozmorov, I., A. Bartke, and R. A. Miller. 2001. Array-based expression analysis of mouse liver genes: effect of age and of the longevity mutant Prop1df. J. Gerontol. Biol. Sci., 56A: B72-B80.